January 18, 2022

In both strains of mice, rapamycin inhibits HCC development and hepatic steatosis (14, 31) Our data demonstrate that starvation-induced LKB1 and AMPK phosphorylation requires TAK1 in hepatocytes, although the mechanism by which TAK1 controls LKB1 and AMPK activities remains elusive (10, 30)

In both strains of mice, rapamycin inhibits HCC development and hepatic steatosis (14, 31) Our data demonstrate that starvation-induced LKB1 and AMPK phosphorylation requires TAK1 …